Afobazol 10 mg (Fabomotizole) 60 tablets

Afobazol 10 mg (Fabomotizole) 60 Tablets

Afobazol is the anxiolytic with fabomotizole — a selective anxiolytic with a fundamentally different mechanism than benzodiazepines: it acts as a sigma-1 receptor agonist and restores the sensitivity of GABA/benzodiazepine receptors under stress conditions, without binding them directly. The practical result is anxiety relief without sedation, without muscle relaxation, without cognitive impairment — and without the dependence and withdrawal syndrome that defines benzodiazepines. In countries where it is registered, Afobazol is used for anxiety states, stress reactions and adaptation disorders in adults — including patients who cannot take or do not want sedating anxiolytics.

What makes fabomotizole different from benzodiazepines

• No sedation — suitable for daytime use: work, driving and concentration stay intact;
• No muscle relaxation — no "heavy body" feeling;
• No memory or cognitive dulling — the known benzodiazepine drawback is absent;
• No dependence or withdrawal — the core benzodiazepine problem (rebound anxiety, tapering battles) does not apply;
• No alcohol potentiation — no dangerous synergy with alcohol typical of benzodiazepines (although alcohol itself is not an anxiety treatment);
• Full effect develops over weeks — this is a course anxiolytic, not an "instant pill": noticeable relief usually builds over 2–4 weeks of daily use.

What it is used for

Afobazol is used (per registered indications and physician guidance) for:

• anxiety states of various origins;
• adaptation disorders (stress of change: relocation, job change, bereavement);
• neurasthenia and stress-related conditions with anxiety component;
• anxiety in patients with somatic diseases where benzodiazepines are undesirable;
• support in smoking cessation programs (anxiety component of nicotine withdrawal).

Important: fabomotizole is not an antipsychotic or antidepressant — for clinical depression, severe anxiety disorders or panic disorder, prescription psychiatric therapy is required. Afobazol addresses the milder anxiety spectrum.

Composition and form

• Active ingredient: fabomotizole 10 mg per tablet;
• Form: 60 tablets, oral route;

How it is used

• Standard adult dose: 10 mg three times daily after meals;
• Maximum daily dose: 30 mg;
• Effect builds gradually — noticeable relief usually after 2–4 weeks of regular use;
• Standard course: 2–4 weeks; longer courses per physician decision;
• Can be combined with other therapies — inform your physician about all medicines you take.

Safety information

• Well tolerated: side effects are uncommon — occasional allergic reactions or headache;
• Not recommended during pregnancy and breastfeeding;
• Does not impair driving or machine operation (no sedation) — but individual reaction should always be observed;
• Not a substitute for psychiatric treatment of severe anxiety, panic disorder or depression;
• If anxiety persists beyond 4–6 weeks despite treatment, consult a physician for reassessment.

FAQ — Frequently Asked Questions

Is Afobazol like a mild benzodiazepine?

No — the mechanism is entirely different. Benzodiazepines directly enhance GABA inhibition (causing sedation, dependence and withdrawal); fabomotizole acts on sigma-1 receptors and modulates stress-response systems without direct GABA binding. The result: anxiety relief without the sedation, cognitive dulling and dependence that define benzodiazepines. It is closer to "stress-adaptation support" than to classic tranquilizers.

When will I feel the effect?

Not immediately — this is the key expectation to set. Unlike benzodiazepines that work in minutes, fabomotizole builds its effect over 2–4 weeks of daily use: anxiety intensity typically decreases gradually, with irritability and tension softening first. Judge the result after a full 4-week course, not after the first tablet.

Can I drive and work while taking it?

Yes — the absence of sedation is one of its defining features. Unlike benzodiazepines, fabomotizole does not slow reaction time or dull concentration in standard studies. Individual sensitivity varies, so observe your own response during the first days, but daytime functioning is generally preserved.

Can I combine Afobazol with other anxiety medicines?

Inform your physician about everything you take. Fabomotizole does not have the dangerous alcohol/depressant synergy of benzodiazepines, but combinations with other anxiolytics, antidepressants or sedatives should still be physician-reviewed. It is often used alongside psychotherapy — a combination that works well.

What if my anxiety is severe — panic attacks, depression?

Afobazol addresses the mild-to-moderate anxiety spectrum and adaptation stress. Clinical depression, panic disorder, generalized anxiety disorder of significant severity require prescription psychiatric therapy — SSRI/SNRI medicines, psychotherapy, or both. Self-treating severe conditions with an OTC anxiolytic delays proper care. See a physician honestly about your symptoms.

Ask a question or inquire about delivery to your country

Telegram

WhatsApp