Samska OD (Tolvaptan) 15 mg 20 tab.

Samska OD (Tolvaptan) 15 mg 20 tab.

Samska is a drug with the active ingredient Tolvaptan, which reduces the level of the hormone that regulates the balance of water and salt (sodium) in the body. High levels of this hormone can cause an imbalance that leads to low sodium levels and fluid retention.

Samska is used to treat hyponatremia (low sodium levels in the blood) in people with heart failure and a certain hormonal imbalance.

Samska improves urine outflow without causing the body to lose too much sodium when urinating.

This guide to the use of the drug contains information about the trademark Samsca - tolvaptan.

Precautions:

You should not use Samsca (tolvaptan) if you have signs of dehydration or problems urinating.

The drug should be taken under the supervision of a doctor.

If you have polycystic kidney disease, do not take the Mask. You should prescribe tolvaptan of another brand (Jynarque) using a special program that provides laboratory monitoring of your liver.

Samska is prescribed to treat low blood sodium levels, but can be dangerous if this condition is eliminated too quickly. Tell your healthcare providers immediately if you have problems with speech or muscle control, difficulty swallowing, difficulty moving your arms and legs, confusion or seizures.

Tolvaptan can cause serious or fatal liver problems. Contact your doctor immediately if you feel unwell and have right-sided upper abdominal pain, vomiting, loss of appetite, or yellowing of your skin or eyes.

You will need frequent medical tests before and during treatment with Samska.

Tell your doctor about all your current medications and any that you start or stop taking. Many drugs can interact, and some drugs should not be used together.

Before taking this medicine

You should not use a Mask if you are allergic to tolvaptan, or if:

You can't urinate;

you can't say you're thirsty; or

you're severely dehydrated and feel like you might pass out.

You should not take Samask if you need to quickly increase the sodium level in your blood.

Some medications may cause undesirable or dangerous effects when used with Male. Your doctor may change your treatment plan if you also use:

nefazodone;

antibiotic - clarithromycin, telithromycin;

antifungal medicine - itraconazole, ketoconazole; or

HIV /AIDS> Medications - indinavir, nelfinavir, ritonavir, saquinavir.

To make sure that Samska is safe for you, tell your doctor if you ever have:

kidney disease or problems with urination;

liver problems;

allergy;

if you drink a lot of alcohol;

if you are malnourished; or

if you are also taking desmopressin (dDAVP), or a diuretic, or "water pills".

It is unknown whether this medicine will harm the unborn child. Tell your doctor if you are pregnant.

You should not breastfeed while taking Samski.

How should I take a Mask?

Take Samska tablets exactly as prescribed by your doctor. Follow all the instructions on your prescription label and read all medication manuals or instructions.

Drink plenty of fluids while taking Samski, but do not drink grapefruit juice or alcoholic beverages.

You can take the pill with or without food.

The mask is usually taken once a day. Follow your doctor's dosing instructions very carefully.

You will need to be monitored in the hospital every time you start or resume treatment with Samska to quickly eliminate any serious side effects. If you stop taking this medicine for any time, do not start taking it again at home.

Prolonged use of tolvaptan can damage your liver. You should not use this medicine for longer than 30 days.

You can easily become dehydrated while taking Samski, which can lead to serious side effects. Consult your doctor if you continue to vomit or have diarrhea, or if you sweat more than usual.

You will need frequent medical tests.

Store at room temperature, away from moisture and heat.

Dosage Information

The usual dose for adults with hyponatremia:

Initial dose: 15 mg orally once a day

Maintenance dose: Increase the dose to 30 mg once a day, at least after 24 hours, to a maximum of 60 mg once a day, as needed to achieve the desired serum sodium level.

Maximum dose: 60 mg once a day

Duration of therapy: maximum 30 days.

The usual dose for adults with hyponatremia, euvolemia:

Initial dose: 15 mg orally once a day

Maintenance dose: Increase the dose to 30 mg once a day, at least after 24 hours, to a maximum of 60 mg once a day, as needed to achieve the desired serum sodium level.

Maximum dose: 60 mg once a day

Duration of therapy: maximum 30 days

Comments:

-During initiation and titration, monitor changes in electrolytes and serum volume frequently.

-Avoid fluid restriction during the first 24 hours of therapy.

-Patients receiving a Mask should be informed that they can continue taking fluids in response to thirst.

Application: Hypervolemic and euvolemic hyponatremia [serum sodium content less than 125 mEq / l or less pronounced hyponatremia, which is symptomatic and cannot be corrected by fluid restriction], including patients with heart failure and syndrome of inappropriate intake of antidiuretic hormone.

Side effects of Samski

Seek emergency medical attention if you have signs of an allergic reaction to boxwood: urticaria; difficulty breathing; swelling of the face, lips, tongue or throat.

Consult a doctor immediately if you have:

weakness, confusion, or feeling dizzy (as if you might lose consciousness);

irregular heartbeat;

unexplained weight loss;

symptoms of dehydration are a feeling of intense thirst or heat, inability to urinate, severe sweating or hot and dry skin; or

liver problems - right-sided pain in the upper abdomen, vomiting, loss of appetite, fever, itching, yellowing of the skin or eyes, poor health.

Samska is prescribed to treat low blood sodium levels, but can be dangerous if sodium levels rise too quickly. Tell your doctor or caregivers immediately if you have any of these signs that your hyponatremia is going away too quickly:

problems with speech or muscle control;

problems with swallowing;

problems with movement of arms and legs;

confusion, mood changes; or

an attack.

Common side effects of Samski may include:

dry mouth;

increased thirst or urination;

feeling hungry, fruity breath;

constipation; or

weakness.

The drug is delivered from Japan and is original.