Sinovial (32 mg/2 ml) – Hyaluronic Acid for Intra-Articular Injection

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Sinovial is a sterile intra-articular viscosupplement containing sodium hyaluronate, designed to restore the natural properties of synovial fluid in patients with degenerative joint disorders. Manufactured in Italy by IBSA, it is intended to improve joint lubrication, reduce pain, and support mobility.

Each prefilled syringe contains 32 mg of sodium hyaluronate in 2 ml (1.6%) and is supplied for single-use administration.

Product Information

• Brand: Sinovial
• Active ingredient: Sodium Hyaluronate
• Strength: 32 mg / 2 ml (1.6%)
• Volume: 2 ml
• Dosage form: Sterile prefilled syringe
• Pack size: One prefilled syringe with sterile needle
• Manufacturer: IBSA, Italy
• Category: Medical device for viscosupplementation

What is Sinovial?

Sinovial is a high-purity sodium hyaluronate solution intended for intra-articular injection. It supplements the natural hyaluronic acid found in synovial fluid, helping restore its viscoelastic properties and supporting smoother joint movement.

It is commonly used in the management of osteoarthritis and other degenerative joint conditions.

How It Works

Following injection into the affected joint, Sinovial helps:

• restore synovial fluid viscosity;
• improve joint lubrication;
• reduce friction between cartilage surfaces;
• absorb mechanical stress;
• support joint mobility;
• relieve pain associated with joint degeneration;
• improve overall joint function.

Indications

Healthcare professionals may recommend Sinovial for:

• Knee osteoarthritis
• Hip osteoarthritis
• Shoulder joint degeneration
• Ankle osteoarthritis
• Degenerative changes in other synovial joints
• Chronic joint pain
• Reduced mobility
• Post-arthroscopic rehabilitation

Treatment should always be based on medical evaluation.

Benefits

• High-purity sodium hyaluronate
• Manufactured in Italy
• Ready-to-use sterile prefilled syringe
• Single-use sterile administration
• Excellent biocompatibility
• Helps restore normal joint lubrication
• Supports mobility and comfort
• Suitable as part of comprehensive osteoarthritis management

Administration

Sinovial must be administered only by a qualified healthcare professional experienced in intra-articular injections.

The treatment schedule depends on:

• affected joint;
• severity of osteoarthritis;
• patient condition;
• physician's recommendations.

Self-injection is not recommended.

Possible Side Effects

Some patients may experience temporary:

• injection-site pain;
• swelling;
• mild redness;
• joint discomfort;
• transient joint effusion.

These reactions are generally short-lived.

Contraindications

Sinovial should not be used in patients with:

• hypersensitivity to any component;
• skin infection at the injection site;
• active joint infection;
• acute inflammatory arthritis unless advised by a physician.

Storage

• Store in the original package.
• Do not freeze.
• Protect from direct sunlight.
• Follow the manufacturer's storage recommendations.
• Keep out of reach of children.

FAQ

What is Sinovial used for?

It is used for viscosupplementation to improve joint lubrication and reduce symptoms associated with osteoarthritis.

What does it contain?

Each syringe contains 32 mg of highly purified sodium hyaluronate in 2 ml.

Can I inject Sinovial myself?

No. The injection should only be performed by a qualified healthcare professional.

When can improvement be expected?

Many patients notice gradual symptom improvement after treatment, although results vary between individuals.

Which joints can be treated?

It is commonly used for the knee but may also be suitable for other synovial joints based on clinical assessment.

Is Sinovial a medicine?

Sinovial is classified as a medical device used for intra-articular viscosupplementation.

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