Adenik 0.4 mg (Tamsulosin) MR — Product Description

Adenik is a preparation containing tamsulosin hydrochloride 0.4 mg in modified-release capsules, manufactured by RafPharmi Co. The product is used in urological practice for male lower urinary tract symptoms associated with benign prostatic hyperplasia (BPH) — the same active substance as the reference brand Omnic, in an accessible formulation.

• Active ingredient: Tamsulosin hydrochloride 0.4 mg per capsule
• Form: modified-release capsules (MR)
• Pack: 30 capsules
• Manufacturer: RafPharmi Co.

Tamsulosin selectively blocks alpha-1A adrenergic receptors concentrated in the prostate, bladder neck and urethra. Blocking these receptors relaxes the smooth muscles around the prostate and bladder outlet: urine flow improves, and BPH symptoms — weak stream, hesitancy, nocturia, incomplete emptying — decrease.

The alpha-1A selectivity is the key advantage: minimal blood-pressure impact compared to non-selective alpha-blockers.

Adenik is prescribed by urologists for:

• treatment of lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia;
• improvement of urine flow and storage symptoms (frequency, nocturia, urgency);
• long-term symptomatic management of BPH.

The medication is prescription-only and used under urologist supervision.

• Standard dose: 1 capsule (0.4 mg) once daily, approximately 30 minutes after the same meal each day (standard tamsulosin MR schedule);
• Swallow whole with water — do not chew or open (modified-release capsule);
• Effect on flow symptoms develops within the first days; full benefit within 2–4 weeks;
• Long-term therapy — duration is determined by the urologist;
• Missed dose: take as soon as remembered the same day; never take a double dose.

• Same active substance as the reference brand Omnic — accessible formulation;
• Selective alpha-1A blockade — minimal blood pressure impact;
• Once-daily regimen;
• Suitable for long-term use under medical supervision.

The most commonly reported adverse reactions:

• dizziness (especially at the start of therapy);
• ejaculation disorders (reversible after discontinuation);
• orthostatic hypotension (rare with selective agents);
• nasal congestion.

Caution with concurrent PDE5 inhibitors (sildenafil, tadalafil) and antihypertensives — combinations are adjusted by the physician. Medical attention should be sought for fainting or severe dizziness.

• Hypersensitivity to tamsulosin or any component;
• Severe liver insufficiency;
• Orthostatic hypotension (history of fainting on standing);
• Concomitant use with strong CYP3A4 inhibitors — physician decision.

Patients undergoing cataract or glaucoma surgery must inform the surgeon about tamsulosin use (intraoperative floppy iris syndrome, IFIS).

FAQ — Frequently Asked Questions

Is Adenik the same as Omnic?

Same active substance — tamsulosin 0.4 mg. Omnic (Astellas) is the original reference brand with the OCAS controlled-release tablet; Adenik (RafPharmi) is an accessible modified-release capsule. Both are European products; the choice is about availability, price and formulation preference.

Food timing: with or without meal?

Standard modified-release tamsulosin capsules are taken approximately 30 minutes after the same meal each day for stable absorption. If your daily routine doesn't allow food-timing, ask your physician about the OCAS tablet form (Omnic Ocas), which is food-independent.

How quickly will urination improve?

Flow improvements often appear within days; full benefit in 2–4 weeks. If symptoms don't improve after a month, the urologist reviews the diagnosis and may add a 5-AR inhibitor (e.g., dutasteride) for long-term prostate-volume reduction.

Can Adenik be combined with Avodart (dutasteride)?

Yes — the alpha-blocker + 5-AR inhibitor combination is a documented standard in moderate-to-severe BPH: tamsulosin addresses symptoms quickly, dutasteride shrinks the prostate long-term. Combination is prescribed and monitored by the urologist.

Is medical consultation necessary?

Yes. Adenik is a prescription medication. Regular urological review, blood pressure control and eye-surgery notification (IFIS) are standard practice.

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