Avodart 0.5 mg (Dutasteride) — Product Description

Avodart is the original GlaxoSmithKline preparation containing dutasteride, a dual 5-alpha-reductase inhibitor. The product is supplied as soft gelatin capsules for oral use and is widely used in urological practice as part of benign prostatic hyperplasia (BPH) management under medical supervision.

• Active ingredient: Dutasteride 0.5 mg per capsule
• Excipients: lecithin, gelatin capsule shell
• Manufacturer: GlaxoSmithKline

• 30 capsules (approximately 1 month of therapy)
• 90 capsules (approximately 3 months of therapy)

Dutasteride blocks both isoforms of the 5-alpha-reductase enzyme (type 1 and type 2), which converts testosterone to dihydrotestosterone (DHT). DHT is the main hormonal driver of prostate growth — reducing its levels shrinks the enlarged prostate and improves urinary symptoms over time.

Unlike finasteride (which blocks only the type 2 isoform), dutasteride provides near-complete suppression of DHT — this is the pharmacological reason urologists choose it in specific clinical scenarios.

Avodart is prescribed by urologists as part of comprehensive therapy in cases of:

• benign prostatic hyperplasia (BPH) with urinary symptoms;
• prostate volume reduction in moderate to severe BPH;
• reduction of acute urinary retention and surgery risk in BPH patients (documented in clinical trials).

The medication is prescription-only and should be used under urologist supervision with periodic monitoring.

• Standard adult dose: 1 capsule (0.5 mg) once daily, with or without food;
• Effect develops gradually: measurable prostate volume reduction typically within 3–6 months;
• Long-term therapy — duration is determined by the urologist;
• Capsules should be swallowed whole (not chewed or opened — the gel can irritate the oral mucosa).

• Original GSK product (not a generic);
• Dual 5-AR inhibition — deeper DHT suppression than finasteride;
• Soft gel capsules, once-daily dosing;
• Documented long-term efficacy in BPH management programs;
• Suitable for long-term use under medical supervision.

The most commonly reported adverse reactions include:

• decreased libido;
• ejaculation disorders;
• rare allergic reactions;
• gynecomastia (breast tenderness/enlargement) in a small percentage of patients.

Most effects are dose-related and reversible after discontinuation. Medical attention should be sought if side effects persist or worsen.

• Hypersensitivity to dutasteride or any component;
• Women and children — the medication is not intended for them;
• Pregnant women should not handle leaking capsules (dutasteride can be absorbed through the skin and may affect male fetus development).

Important: dutasteride remains detectable in blood for 4–6 months after discontinuation — a blood donation should be avoided for at least 6 months after the last dose.

FAQ — Frequently Asked Questions

What is the difference between Avodart and Proscar (finasteride)?

Both reduce DHT, but via different mechanisms: finasteride blocks only type 2 5-alpha-reductase, while dutasteride blocks both type 1 and type 2 — resulting in deeper DHT suppression. The choice between them is made by the urologist based on the clinical scenario.

How long does it take to see an effect?

Urinary symptoms improve gradually. Prostate volume reduction becomes measurable after 3–6 months of continuous therapy. Full effect may take up to 12 months.

Should I choose 30 or 90 capsules?

Therapy is long-term: 30 capsules cover about one month, 90 capsules about three months. Patients on stable maintenance therapy typically benefit from the larger pack. The starting period is usually covered by 30-capsule packs until the dose is confirmed.

Can Avodart be used for hair loss?

Dutasteride is not approved for androgenetic alopecia in most jurisdictions; finasteride has the formal indication. Any off-label use must be discussed with a physician — this product page describes approved urological indications only.

Is medical consultation necessary?

Yes. Avodart is a prescription medication. Regular monitoring (PSA, prostate assessment) during therapy is standard urological practice.

Ask a question or inquire about delivery to your country

Telegram

WhatsApp