OEstrodose 0.06% Gel 80 g (Estradiol)

OEstrodose 0.06% Gel — 80 g (Estradiol), Besins Healthcare

Estrodose (Oestrodose) by Besins Healthcare is transdermal 17-beta-estradiol gel 0.06% with a metered pump - the original French menopause therapy. Each pump press delivers 1.25 g of gel containing 0.75 mg estradiol; the 80 g bottle provides 64 doses.

Composition

• 17-beta Estradiol - 0.06 g per 100 g of gel
• Pump pack: 80 g (100 ml), 64 metered doses of 1.25 g / 0.75 mg each
• Excipients: carbomer, trolamine, ethanol, purified water

Why a transdermal gel

Estradiol applied to the skin passes directly into the bloodstream, bypassing first-pass liver metabolism - the same principle as in patches, but with flexible dosing. The pump allows precise adjustment: from 1 to 4 doses per day, per the physician scheme. Transdermal estradiol is associated with a lower venous thrombosis risk profile than oral estrogens in modern HRT practice.

Dosing (per instructions)

• Usual starting dose: 2 pumps/day = 2.5 g gel = 1.5 mg estradiol, daily during 24-28 days of the month
• Adjustment: reduce to 1 pump or increase to 3-4 pumps (max 3.0 mg/day) depending on symptom response - per physician
• Apply to clean dry skin of arms/shoulders/thighs, rotate sites daily; let dry before dressing
• With a uterus: progesterone must be combined (e.g., Progestan capsules) to protect the endometrium - per the HRT scheme
• Wash hands after application; do not apply to breasts or irritated skin

Where Estrodose is used

• Menopausal symptoms: hot flushes, night sweats, sleep disturbance, vaginal dryness
• Estrogen-deficiency mood and cognitive complaints (within HRT)
• Osteoporosis prevention in postmenopause (per physician assessment)

Product features

• Original Besins Healthcare product (France) - the world reference in estradiol gels
• Metered pump - precise daily dose tailoring
• 64 doses = about 1 month of standard 2-pump dosing

Contraindications

Known or suspected hormone-dependent tumors; undiagnosed genital bleeding; active thromboembolic disease; severe liver disorders; hypersensitivity. HRT requires physician evaluation with annual benefit/risk review.

FAQ

Estrodose vs Oestrogel - what is the difference?

Both are Besins estradiol gels with the same 0.06% concentration and the same 1.25 g/0.75 mg pump dose. Estrodose (Oestrodose) is the French-market presentation; Oestrogel is the international brand. Same molecule, same dosing math.

Do I need progesterone with it?

If the uterus is intact - yes: estrogen alone stimulates endometrial growth, so progesterone (e.g., Progestan micronized capsules) is combined per the HRT scheme. After hysterectomy, estrogen monotherapy is typically prescribed.

Where exactly to apply the gel?

Arms, shoulders or thighs - rotating sites daily. Not on the breasts, face or irritated skin. Apply once daily after showering, let it dry for a few minutes.

Can someone touch the application site?

Let the gel dry and cover the area; estradiol can transfer by skin contact - avoid direct skin-to-skin contact with the application site, especially with children or pets, until the skin is covered or washed.

How long before the effect?

Hot flushes usually improve within the first 2 weeks of correct dosing; full symptom assessment and dose adjustment are done after 2-3 months per the HRT schedule.

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